Institute of Fisheries Science, NTU

研究重點：

(1)日本鰻人工繁殖研究。
(2)激素誘導性腺發育過程之變化。
(3)DNA甲基化與微小RNA對於生殖細胞之分子機制影響。
(4)由次世代定序(Next generation sequencing)檢測及量化生殖和體細胞基因組遺傳變異。

Reuy-Tay Lin, Edward Hsi, Hsiu-Fen Lin, Yi-Chu Liao, Yung-Song Wang, Suh-Hang H. Juo (2014, Feb). LINE-1 Methylation is Associated with an Increased Risk of Ischemic Stroke in Men. Current Neurovascular Research, 11(1)4-9.

Yi-Chu Liao, Yung-Song Wang, Yuh-Cherng Guo, Wen-Lien Lin, Ming-Hung Chang, Suh-Hang Hank Juo. (2013, Nov). Let-7g improves multiple endothelial functions through targeting tgf-£] and sirt-1 signaling . Journal of the American College of Cardiology, doi: 10.1016/j.jacc.2013.09.069..

Wen-Wen Chou, Ku-Chung Chen, Yung-Song Wang, Jaw-Yuan Wang, Chung-Ling Liang, Suh-Hang Hank Juo (2013, Sep). The role of SIRT1/AKT/ERK pathway in ultraviolet B induced damage on human retinal pigment epithelial cells. Toxicology in vitro, 27(6), 1728-1736.

Pei-Chien Tsai, Yi-Chu Liao, Yung-Song Wang, Hsiu-Fen Lin, Ruey-Tay Lin, Suh-Hang Hank Juo (2013, Aug). Serum microRNA-21 and microRNA-221 as potential biomarkers for cerebrovascular disease. . Journal of vascular research, 50(4), 346-354 .

Mu-En Liu, Yi-Chu Liao, Ruey-Tay Lin, Yung-Song Wang, Edward Hsi, Hsiu-Fen Lin, Ku-Chung Chen, Suh-Hang H. Juo (2013, May). A functional polymorphism of PON1 interferes with microRNA binding to increase the risk of ischemic stroke and carotid atherosclerosis. Atherosclerosis, 228(1), 161-167.

Eing-Mei Tsai, Yung-Song Wang, Chang-Shen Lin, Wen-Yin Lin, Edward Hsi, Ming-Tsang Wu, Suh-Hang H Juo (2013, Apr). A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women . Journal of Human genetics, 58: 202-209.

Yung-Song Wang, Hay-Yan J.Wang, Yi-Chu Liao, Pei-Chien Tsai, Ku-Chung Chen, Hsin-Yun Cheng, Ruey-Tay Lin, Suh-Hang Hank Juo (2012, Sep). MicroRNA-195 regulates vascular smooth muscle cell phenotypes and prevents neointimal formation. CARDIOVASCULAR RESEARCH, 95, 517-526.

Ku-Chung Chen, Yi-Chu Liao, I-Chung Hsieh, Yung-Song Wang, Ching-Yu Hu, Suh-Hang Hank Juo (2012, Jan). OxLDL causes both epigenetic modification and signaling regulation on the microRNA-29b gene: Novel mechanisms for cardiovascular diseases. , 52, 587

Wen-Wen Chou, Yung-Song Wang, Ku-Chung Chen, Jing-Mei Wu, Chung-Ling Liang, Suh-Hang Hank Juo (2012, Jan). Tannic acid suppresses ultraviolet B-induced inflammatory signaling and complement factor B on human retinal pigment epithelial cells . CELLULAR IMMUNOLOGY, 273,79

 Yung-Song Wang, Wen-Wen Chou, Ku-Chung Chen, Hsin-Yun Cheng, Ruey-Tay Lin, Suh-Hang Hank Juo (2012, Jan). microRNA-152 Mediates DNMT1Regulated DNA Methylation in the Estrogen Receptor a Gene. PLoS One, 7, 110.

Yi-Chu Liao, Yung-Song Wang, Yuh-Cherng Guo, Kouichi Ozaki,Toshihiro Tanaka,Hsiu-Fen Lin, Ming-Hong Chang, Ku-Chung Chen, Ming-Lung Yu, Sheng-Hsiung Sheu, Suh-Hang Hank Juo (2011, Sep). BRAP Activates Inflammatory Cascades and Increases the Risk for Carotid Atherosclerosis . MOLECULAR MEDICINE, 17, 1065-1074.

Ku-Chung Chen, I-Chung Hsieh, Edward Hsi, Yung-Song Wang, Chia-Yen Dai, Wen-Wen Chou, Suh-Hang Hank Juo (2011, Aug). Negative feedback regulation between microRNA let-7g and the oxLDL receptor LOX-1. JOURNAL OF CELL SCIENCE, 124, 4115-4124.
13. Chung-Ling Liang, Edward Hsi, Ku-Chung Chen, Yun-Ru Pan, Yung-Song Wang, Suh-Hang Hank Juo (2011, May). A functional polymorphism at 3UTR of the PAX6 gene may confer risk for extreme myopia in the Chinese . INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 52, 3500-3505.

Ku-Chung Chen, Yung-Song Wang, Ching-Yu Hu, Wei-Chiao Chang,Yi-Chu Liao,Chia-Yen Dai,Suh-Hang Hank Juo (2011, May). OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases. FASEB JOURNAL, 25, 1718-1728.

Pei-Chien Tsai, Tsung-Hsien Lin, Po-Chao Hsu, Yung-Song Wang, Yi-Chu Liao, Suh-Hang Hank Juo (2011, Jan). Polymorphism of 270 A¡ÖG in BRAP is associated with Lower Ankle-Brachial Index in a Taiwanese population . Journal of Atherosclerosis and Thrombosis, 18, 413-420.

Yung-Song Wang, Ruey-Tay Lin, Hsin-Yun Cheng, Sheau-Fang Yang, Wen-Wen Chou, Suh-Hang Hank Juo (2011, Jan). Anti-atherogenic effect of San-HuangXie-Xin-Tang, a traditional Chinese medicine, in cultured human aortic smooth muscle cells. JOURNAL OF ETHNOPHARMACOLOGY, 133, 442

Wei-Chiao Chang, Chen-Chia Chang, Yung-Song Wang, Yu-Shiuan Wang, Wei-Teng Weng, Tohru Yoshioka, Suh-Hang Hank Juo (2010, Oct). Involvement of the epidermal growth factor receptor in Pb2+-induced activation of cPLA2/COX-2 genes and PGE2 production in vascular smooth muscle cells. TOXICOLOGY, 279, 45