台大化工系網站英文版-陳賢燁教授 / Hsien-Yeh Chen Professor

Introduction
Honor
Publications
Introduction
Education Background

National Taiwan University B.S. Ch.E. 1999

University of Michigan M.S. Ch.E. 2004

University of Michigan Ph.D. Ch.E. 2008

Research Topic

Biointerface Engineering
Latest advancements in biomaterials aim to control biological responses. The critical criteria for designing biointerfaces include controlled properties of biomolecules, non-fouling, compatibility with microfabrication, accessible within microgeometries, applicability on 3-D objects, defined microstructures, cell/surface responses, biodegradability, and the ability to create surface gradient. Our group has focused on engineering of biointerface by using vapor-based reactive polymers. Recent works include:

Biomimetic Surface Modifications

Biomolecular Engineering and Surface Bioconjugate Chemistries

Biomedical Coating Applications
Honor
指導學生吳亭瑩(博士生)，李沁芸(碩士生)，蕭家麒(碩士生)，「新型可調控光學特性及生物功能之人工水晶體」，2020年經濟部技術處第10屆搶鮮大賽創業規劃類，亞軍。

指導張育銘(碩士生)，胡書嫚(碩士生)，張乃云(計畫研究員)，「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置」，2020年經濟部技術處第10屆搶鮮大賽創業規劃類，冠軍。

2021 第十七屆IIP國際傑出發明家-學術國光獎章。

2021 第十七屆IIP國際傑出發明家-學術國光獎章。

2021 行政院環保署-第2屆綠色化學應用及創新獎。

2021 The SCEJ (日本) Award for Outstanding Asian Researcher and Engineer。

陳賢燁帶領團隊: 吳亭瑩(博士生)，張育銘(碩士生)，蕭家麒(碩士生)，李沁芸(碩士生)，胡書嫚(碩士生)，草彅達也(碩士生)，魏婉瑩(大學生)，張乃云(計畫研究員)，吳治宇(博士後研究員)，楊晏清(博士後研究員)，黃晁瑋(博士後研究員)，「多功能之硬骨及軟骨組織修復裝置」，2021年化學產業菁英獎榮獲「卓越研發獎」。

指導學生張育銘(碩士生)，胡書嫚(碩士生)，草彅達也(碩士生)，張乃云(計畫研究員)，「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置，2021年第三屆綠點子國際發明暨設計競賽，鈦金獎。

指導學生吳亭瑩(博士生)，李沁芸(碩士生)，蕭家麒(碩士生)，魏婉瑩(碩士生)，「新型可調控光學特性及生物功能之人工水晶體」，2021年第三屆綠點子國際發明暨設計競賽，鈦金獎。

指導學生吳亭瑩(博士生)，李沁芸(博士生)，蕭家麒(碩士生)，魏婉瑩(學士生)，「新型可調控光學特性及生物功能之人工水晶體」，2021年十七屆烏克蘭國際發明展，金牌獎。

指導學生張育銘(碩士生)，胡書嫚(碩士生)，草彅達也(碩士生)，張乃云(計畫研究員)，王允杉(實習生)，「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置，2021年第十五屆波蘭國際發明展，金牌獎。

指導學生張育銘(碩士生)，胡書嫚(碩士生)，草彅達也(碩士生)，張乃云(計畫研究員)，王允杉(實習生)，「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置」，2021香港創新科技國際發明展，金牌獎。

指導學生張育銘(碩士生)，胡書嫚(碩士生)，草彅達也(碩士生)，「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置」，2021年華立創新材料大賽，金質獎。

指導學生林彥勳(碩士生)，吳易倡(碩士生)，陳諭萱(碩士生)，林奕維(大學專題生)，「氣相沉積製程技術創建多功能濾水裝置」，2022年馬來西亞MTE發明，金牌獎。

指導學生張育銘(碩士生)，胡書嫚(碩士生)，草彅達也(碩士生)，「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置」，2022年第二十五屆莫斯科阿基米德國際發明展，金牌獎。

2022年生策會國家新創獎:「新型可調控光學特性及生物功能之人工水晶體」。
Publications
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Yao-Tsung Hsu, Chih-Yu Wu, Zhen-Yu Guan, Ho-Yi Sun, Chieh Mei, Wen Chien Chen, Nai-Chen Cheng, Jiashing Yu, Hsien-Yeh Chen* “Characterization of Mechanical Stability and Immunological Compatibility for Functionalized Modification Interfaces,” Scientific Reports, 9, 7644 (2019). (IF: 3.998)

Yu-Chih Chiang, Cuei-Ping Ho, Yin-Lin Wang, Po-Chun Chen, Peng-Yuan Wang, Hsien-Yeh Chen* “Vapor-Deposited Reactive Coating with Chemically and Topographically Erasable Properties,” Polymers, 11, 1595 (2019). (IF: 4.284)

Kao-Chun Tang, Kai-Chiang Yang, Che-Wei Lin, Yi-Kai Chen, Ting-Yu Lu, Hsien-Yeh Chen, Nai-Chen Cheng, Jiashing Yu* (2019, Oct). Human Adipose Derived Stem Cell Secreted Extracellular Matrix Incorporated into Electrospun Poly(Lactic-co-Glycolic Acid) Nanofibrous Dressing for Enhancing Wound Healing,” Polymers, 11, 1609 (2019). (IF: 4.284)

Ya-Ru Chiu, Yao-Tsung Hsu, Chih-Yu Wu, Tzu-Hung Lin, Yu-Zhen Yang, Hsien-Yeh Chen* “Fabrication of Asymmetrical and Gradient Hierarchy Structures of Poly-p-xylylenes on Multiscale Regimes Based on A Vapor-Phase Sublimation and Deposition Process,” Chemistry of Materials, 32, 1120-1130 (2020). (IF: 9.451)

Yue Shi, Kun Liu, Xuelian Tao, Zhen Zhang, Hsien-Yeh Chen*, Peng-Yuan Wang* “Decoration of Material Surfaces with Complex Physicochemical Signals for Biointerface Applications,” ACS Biomaterials Science & Engineering, accepted (2020). (Review Paper) (IF: 4.152)

C.-W. Lin, Z.-Y. Guan, M. Lu, T.-Y. Wu, N.-C. Cheng, H.-Y. Chen*, J. Yu, Synergistically Enhanced Wound Healing of a Vapor-Constructed Porous Scaffold, ACS Applied Bio Materials, 3 (2020) 5678-5686. (IF: 3.25)

Y. Shi, K. Liu, Z. Zhang, X. Tao, H.-Y. Chen*, P. Kingshott, P.-Y. Wang, Decoration of Material Surfaces with Complex Physicochemical Signals for Biointerface Applications, ACS Biomaterials Science & Engineering, 6 (2020) 1836-1851. (IF: 4.152)

C.-Y. Wu, C.-L. Guo, Y.-C. Yang, C.-W. Huang, J.-Y. Zeng, Z.-Y. Guan, Y.-C. Chiang, P.-Y. Wang, H.-Y. Chen*, Parylene-Based Porous Scaffold with Functionalized Encapsulation of Platelet-Rich Plasma and Living Stem Cells for Tissue Engineering Applications, ACS Applied Bio Materials, 3 (2020) 7193-7201. (IF: 3.25)

T.-Y. Wu, C. Gao, M.-C. Huang, Z. Zhang, P.-Y. Wang, H.-Y. Chen*, G. Chen, H.-Y. Chen, Vapor-Stripping and Encapsulating to Construct Particles with Time-Controlled Asymmetry and Anisotropy, Coatings, 10(12), 1248 (2020). (IF: 2.896)

H.-Y. Chen*, P.-Y. Wang, Special Issue: Biointerface Coatings for Biomaterials and Biomedical Applications, Coatings, 11(4), 423 (2021). (IF: 2.896)

S.-M. Hu, C.-Y. Lee, Y.-M. Chang, J.-Q. Xiao, T. Kusanagi, T.-Y. Wu, N.-Y. Chang, J. Christy, Y.-R. Chiu, C.-W. Huang, Y.-C. Yang, Y.-C. Chiang, H.-Y. Chen*, Vapor-Phase Fabrication of a Maleimide-Functionalized Poly-p-xylylene with a Three-Dimensional Structure, Coatings, 11(4): 466. (2021). (IF: 2.896)

C.-Y. Lee, S.-M. Hu, J.-Q. Xiao, Y.-M. Chang, T. Kusanagi, T.-Y. Wu, Y.-R. Chiu, Y.-C. Yang, C.-W. Huang, H.-Y. Chen*, Vapor Sublimation and Deposition to Fabricate a Porous Methyl Propiolate-Functionalized Poly-p-xylylene Material for Copper-Free Click Chemistry, Polymers, 13 (2021). (IF: 4.284)

Y.-C. Yang, W.-S. Huang, S.-M. Hu, C.-W. Huang, C.-H. Chiu, H.-Y. Chen*, Synergistic and Regulatable Bioremediation Capsules Fabrication Based on Vapor-Phased Encapsulation of Bacillus Bacteria and its Regulator by Poly-p-Xylylene, Polymers, 13 (2021). (IF: 4.284)

C.-Y. Wu, T.-Y. Wu, Z.-Y. Guan, P.-Y. Wang, Y.-C. Yang, C.-W. Huang, T.-H. Lin, H.-Y. Chen*, Vapor-Phased Fabrication and Modulation of Cell-laden Scaffolding Materials, Nature Communications, DOI: 10.1038/s41467-021-23776-8. (2021) (Multidisciplinary Sciences: 3/64=4.7%, IF: 15.805)

T.-Y. Wu, C.-Y. Wu, J. Christy, Y.-C. Chiang, Z.-Y. Guan, J.-S. Yu, H.-Y. Chen*. "Vapor‐Phase Fabrication of Cell‐Accommodated Scaffolds with Multicomponent Functionalization for Neuronal Applications." Advanced Materials Interfaces 8.24 (2021): 2100929. (IF: 6.389)

C.-Y. Wu, Y.-C. Chiang, J. Christy, P.-H. Huang, N.-Y. Chang, Wenny, Y.-C. Chiu, Y.-C. Yang, P.-C. Chen, P.-Y. Wang, H.-Y. Chen*, "Guiding Stem Cell Differentiation and Proliferation Activities Based on Nanometer-Thick Functionalized Poly-p-xylylene Coatings." Coatings 11.5 (2021): 582. (IF: 3.236)

Y.-C. Chiang, H.-W. Yeh, S.-M. Hu, C.-Y. Wu, T.-Y. Wu, C.-H. Chen, P.-C. Liao, Z.-Y. Guan, N.-C. Cheng*, H.-Y. Chen* “Vapor construction and modification of stem cell-laden multicomponent scaffolds for regenerative therapeutics“, Materials Today Bio, 13, 100213 (2022). (Engineering, Biomedical: 11/98=11.2%, IF: 10.761)

Y.-M. Chang, J.-Q. Xiao, J. Christy, C.-Y. Wu, C.-W. Huang, T.-Y. Wu, Y.-C. Chiang, T.-H. Lin, H.-Y. Chen* “Ice-templated synthesis of multicomponent porous coat-ings via vapour sublimation and deposition polymerization,” Materials Today Bio, 16, 100403 (2022). (Engineering, Biomedical: 11/98=11.2%, IF: 10.761)

T.-Y. Wu, T.-H. Lin, and H.-Y. Chen* "Controlling the asymmetry of densified and porous hybrid coatings based on vapor sublimation and deposition." Materials Today Advances, 16, 100292 (2022). (IF: 9.918)

C.‐Y. Lee, S.-M. Hu, J. Christy, F.-Y. Chou, T.-C. Ramli, H.-Y. Chen* "Biointerface Coatings With Structural and Biochemical Properties Modifications of Biomaterials." Advanced Materials Interfaces, 2202286 (2023). (IF: 6.389)

台大化工系網站英文版

陳賢燁 教授 / Hsien-Yeh Chen Professor

陳賢燁 教授 / Hsien-Yeh Chen Professor

陳賢燁教授 / Hsien-Yeh Chen Professor

陳賢燁教授 / Hsien-Yeh Chen Professor