Skip to main content

台大化工系網站英文版

陳賢燁 教授 / Hsien-Yeh Chen Professor

生物界面及先進醫材實驗室 Biointerface Engineering Lab 二館 氣相功能性高分子薄膜生物表面界面工程 Biointerface Engineering (02)3366-9476 BLDG.II (02)3366-1454 hsychen@ntu.edu.tw N407 陳賢燁 Hsien-Yeh Chen 化工二館(鄭江樓) CheE BLDG.II 教授 Professor N410
    • Education Background
      • National Taiwan University  B.S. Ch.E. 1999
      • University of Michigan M.S. Ch.E. 2004
      • University of Michigan Ph.D. Ch.E. 2008

     

    • Research Topic
      • Biointerface Engineering
        Latest advancements in biomaterials aim to control biological responses. The critical criteria for designing biointerfaces include controlled properties of biomolecules, non-fouling, compatibility with microfabrication, accessible within microgeometries, applicability on 3-D objects, defined microstructures, cell/surface responses, biodegradability, and the ability to create surface gradient. Our group has focused on engineering of biointerface by using vapor-based reactive polymers. Recent works include:
        • Biomimetic Surface Modifications
        • Biomolecular Engineering and Surface Bioconjugate Chemistries
        • Biomedical Coating Applications
    1. 指導學生吳亭瑩(博士生),李沁芸(碩士生),蕭家麒(碩士生),「新型可調控光學特性及生物功能之人工水晶體」,2020年經濟部技術處第10屆搶鮮大賽創業規劃類,亞軍。
    2. 指導張育銘(碩士生),胡書嫚(碩士生),張乃云(計畫研究員),「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置」,2020年經濟部技術處第10屆搶鮮大賽創業規劃類,冠軍。
    3. 2021 第十七屆IIP國際傑出發明家-學術國光獎章。
    4. 2021 第十七屆IIP國際傑出發明家-學術國光獎章。
    5. 2021 行政院環保署-第2屆綠色化學應用及創新獎。
    6. 2021 The SCEJ (日本) Award for Outstanding Asian Researcher and Engineer。
    7. 陳賢燁帶領團隊: 吳亭瑩(博士生),張育銘(碩士生),蕭家麒(碩士生),李沁芸(碩士生),胡書嫚(碩士生),草彅達也(碩士生),魏婉瑩(大學生),張乃云(計畫研究員),吳治宇(博士後研究員),楊晏清(博士後研究員),黃晁瑋(博士後研究員),「多功能之硬骨及軟骨組織修復裝置」,2021年化學產業菁英獎榮獲「卓越研發獎」。
    8. 指導學生張育銘(碩士生),胡書嫚(碩士生),草彅達也(碩士生),張乃云(計畫研究員),「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置,2021年第三屆綠點子國際發明暨設計競賽,鈦金獎。
    9. 指導學生吳亭瑩(博士生),李沁芸(碩士生),蕭家麒(碩士生),魏婉瑩(碩士生),「新型可調控光學特性及生物功能之人工水晶體」,2021年第三屆綠點子國際發明暨設計競賽,鈦金獎。
    10. 指導學生吳亭瑩(博士生),李沁芸(博士生),蕭家麒(碩士生),魏婉瑩(學士生),「新型可調控光學特性及生物功能之人工水晶體」,2021年十七屆烏克蘭國際發明展,金牌獎。
    11. 指導學生張育銘(碩士生),胡書嫚(碩士生),草彅達也(碩士生),張乃云(計畫研究員),王允杉(實習生),「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置,2021年第十五屆波蘭國際發明展,金牌獎。
    12. 指導學生張育銘(碩士生),胡書嫚(碩士生),草彅達也(碩士生),張乃云(計畫研究員),王允杉(實習生),「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置」,2021香港創新科技國際發明展,金牌獎。
    13. 指導學生張育銘(碩士生),胡書嫚(碩士生),草彅達也(碩士生),「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置」,2021年華立創新材料大賽,金質獎。
    14. 指導學生林彥勳(碩士生),吳易倡(碩士生),陳諭萱(碩士生),林奕維(大學專題生),「氣相沉積製程技術創建多功能濾水裝置」,2022年馬來西亞MTE發明,金牌獎。
    15. 指導學生張育銘(碩士生),胡書嫚(碩士生),草彅達也(碩士生),「氣相結構操控製程創建多功能之硬骨及軟骨組織修復裝置」,2022年第二十五屆莫斯科阿基米德國際發明展,金牌獎。
    16. 2022年 生策會國家新創獎:「新型可調控光學特性及生物功能之人工水晶體」。
    1. Yao-Tsung Hsu, Chih-Yu Wu, Zhen-Yu Guan, Ho-Yi Sun, Chieh Mei, Wen Chien Chen, Nai-Chen Cheng, Jiashing Yu, Hsien-Yeh Chen* “Characterization of Mechanical Stability and Immunological Compatibility for Functionalized Modification Interfaces,” Scientific Reports, 9, 7644 (2019). (IF: 3.998)
    2. Yu-Chih Chiang, Cuei-Ping Ho, Yin-Lin Wang, Po-Chun Chen, Peng-Yuan Wang, Hsien-Yeh Chen* “Vapor-Deposited Reactive Coating with Chemically and Topographically Erasable Properties,” Polymers, 11, 1595 (2019). (IF: 4.284)
    3. Kao-Chun Tang, Kai-Chiang Yang, Che-Wei Lin, Yi-Kai Chen, Ting-Yu Lu, Hsien-Yeh Chen, Nai-Chen Cheng, Jiashing Yu* (2019, Oct). Human Adipose Derived Stem Cell Secreted Extracellular Matrix Incorporated into Electrospun Poly(Lactic-co-Glycolic Acid) Nanofibrous Dressing for Enhancing Wound Healing,” Polymers, 11, 1609 (2019). (IF: 4.284)
    4. Ya-Ru Chiu, Yao-Tsung Hsu, Chih-Yu Wu, Tzu-Hung Lin, Yu-Zhen Yang, Hsien-Yeh Chen* “Fabrication of Asymmetrical and Gradient Hierarchy Structures of Poly-p-xylylenes on Multiscale Regimes Based on A Vapor-Phase Sublimation and Deposition Process,” Chemistry of Materials, 32, 1120-1130 (2020). (IF: 9.451)
    5. Yue Shi, Kun Liu, Xuelian Tao, Zhen Zhang, Hsien-Yeh Chen*, Peng-Yuan Wang* “Decoration of Material Surfaces with Complex Physicochemical Signals for Biointerface Applications,” ACS Biomaterials Science & Engineering, accepted (2020). (Review Paper) (IF: 4.152)
    6. C.-W. Lin, Z.-Y. Guan, M. Lu, T.-Y. Wu, N.-C. Cheng, H.-Y. Chen*, J. Yu, Synergistically Enhanced Wound Healing of a Vapor-Constructed Porous Scaffold, ACS Applied Bio Materials, 3 (2020) 5678-5686. (IF: 3.25)
    7. Y. Shi, K. Liu, Z. Zhang, X. Tao, H.-Y. Chen*, P. Kingshott, P.-Y. Wang, Decoration of Material Surfaces with Complex Physicochemical Signals for Biointerface Applications, ACS Biomaterials Science & Engineering, 6 (2020) 1836-1851. (IF: 4.152)
    8. C.-Y. Wu, C.-L. Guo, Y.-C. Yang, C.-W. Huang, J.-Y. Zeng, Z.-Y. Guan, Y.-C. Chiang, P.-Y. Wang, H.-Y. Chen*, Parylene-Based Porous Scaffold with Functionalized Encapsulation of Platelet-Rich Plasma and Living Stem Cells for Tissue Engineering Applications, ACS Applied Bio Materials, 3 (2020) 7193-7201. (IF: 3.25)
    9. T.-Y. Wu, C. Gao, M.-C. Huang, Z. Zhang, P.-Y. Wang, H.-Y. Chen*, G. Chen, H.-Y. Chen, Vapor-Stripping and Encapsulating to Construct Particles with Time-Controlled Asymmetry and Anisotropy, Coatings, 10(12), 1248 (2020). (IF: 2.896)
    10. H.-Y. Chen*, P.-Y. Wang, Special Issue: Biointerface Coatings for Biomaterials and Biomedical Applications, Coatings, 11(4), 423 (2021). (IF: 2.896)
    11. S.-M. Hu, C.-Y. Lee, Y.-M. Chang, J.-Q. Xiao, T. Kusanagi, T.-Y. Wu, N.-Y. Chang, J. Christy, Y.-R. Chiu, C.-W. Huang, Y.-C. Yang, Y.-C. Chiang, H.-Y. Chen*, Vapor-Phase Fabrication of a Maleimide-Functionalized Poly-p-xylylene with a Three-Dimensional Structure, Coatings, 11(4): 466. (2021). (IF: 2.896)
    12. C.-Y. Lee, S.-M. Hu, J.-Q. Xiao, Y.-M. Chang, T. Kusanagi, T.-Y. Wu, Y.-R. Chiu, Y.-C. Yang, C.-W. Huang, H.-Y. Chen*, Vapor Sublimation and Deposition to Fabricate a Porous Methyl Propiolate-Functionalized Poly-p-xylylene Material for Copper-Free Click Chemistry, Polymers, 13 (2021). (IF: 4.284)
    13. Y.-C. Yang, W.-S. Huang, S.-M. Hu, C.-W. Huang, C.-H. Chiu, H.-Y. Chen*, Synergistic and Regulatable Bioremediation Capsules Fabrication Based on Vapor-Phased Encapsulation of Bacillus Bacteria and its Regulator by Poly-p-Xylylene, Polymers, 13 (2021). (IF: 4.284)
    14. C.-Y. Wu, T.-Y. Wu, Z.-Y. Guan, P.-Y. Wang, Y.-C. Yang, C.-W. Huang, T.-H. Lin, H.-Y. Chen*, Vapor-Phased Fabrication and Modulation of Cell-laden Scaffolding Materials, Nature Communications, DOI: 10.1038/s41467-021-23776-8. (2021) (Multidisciplinary Sciences: 3/64=4.7%, IF: 15.805)
    15. T.-Y. Wu, C.-Y. Wu, J. Christy, Y.-C. Chiang, Z.-Y. Guan, J.-S. Yu, H.-Y. Chen*. "Vapor‐Phase Fabrication of Cell‐Accommodated Scaffolds with Multicomponent Functionalization for Neuronal Applications." Advanced Materials Interfaces 8.24 (2021): 2100929. (IF: 6.389)
    16. C.-Y. Wu, Y.-C. Chiang, J. Christy, P.-H. Huang, N.-Y. Chang, Wenny, Y.-C. Chiu, Y.-C. Yang, P.-C. Chen, P.-Y. Wang, H.-Y. Chen*, "Guiding Stem Cell Differentiation and Proliferation Activities Based on Nanometer-Thick Functionalized Poly-p-xylylene Coatings." Coatings 11.5 (2021): 582. (IF: 3.236)
    17. Y.-C. Chiang, H.-W. Yeh, S.-M. Hu, C.-Y. Wu, T.-Y. Wu, C.-H. Chen, P.-C. Liao, Z.-Y. Guan, N.-C. Cheng*, H.-Y. Chen* “Vapor construction and modification of stem cell-laden multicomponent scaffolds for regenerative therapeutics“, Materials Today Bio, 13, 100213 (2022). (Engineering, Biomedical: 11/98=11.2%, IF: 10.761)
    18. Y.-M. Chang, J.-Q. Xiao, J. Christy, C.-Y. Wu, C.-W. Huang, T.-Y. Wu, Y.-C. Chiang, T.-H. Lin, H.-Y. Chen* “Ice-templated synthesis of multicomponent porous coat-ings via vapour sublimation and deposition polymerization,” Materials Today Bio, 16, 100403 (2022). (Engineering, Biomedical: 11/98=11.2%, IF: 10.761)
    19. T.-Y. Wu, T.-H. Lin, and H.-Y. Chen* "Controlling the asymmetry of densified and porous hybrid coatings based on vapor sublimation and deposition." Materials Today Advances, 16, 100292 (2022). (IF: 9.918)
    20. C.‐Y. Lee, S.-M. Hu, J. Christy, F.-Y. Chou, T.-C. Ramli, H.-Y. Chen* "Biointerface Coatings With Structural and Biochemical Properties Modifications of Biomaterials." Advanced Materials Interfaces, 2202286 (2023). (IF: 6.389)