台大化工系網站英文版-蔡偉博教授 / Wei-Bor Tsai Professor

Introduction
Publications
Introduction
Education Background

National Taiwan University B.S. Ch.E. ，1983

National Taiwan University M.S. Biochemistry ，1991

University of Washington Ph. D. Bioengineering，1999

Research Topic

Surface modification of biomaterials for improvement in biocompatibility:
development of new surface modification techniques to enhance biomaterials’ biocompatibility with respect to cell affinity or anti-fouling ability.

Cell responses to surface topographies:
investigation of the effects of surface micro-/nano-metric topographies on cell morphology, adhesion, growth and differentiation in order to control cell behaviors and apply to tissue engineering.

Biomaterial development for tissue engineering applications:
development of scaffolds in the form of hydrogels or nanofibers, that are incorporated with active biomolecules for cell growth and differentiation.

Recent Research Topic

紡織產業卓越創新研究中心業務推展 NT$ 400,000, 紡織研究所, 04/01/2009-12/31/2009

製備具有微圖樣的聚電解質多層膜及其在細胞工程的應用 NT$ 970,000, 97-2628-E-002-028-MY2, 08/01/2009-07/31/2010
Publications
View detailed information on publications from the past five years, please click here!

R. Chang and W. B. Tsai, “Fabrication of Photothermo-Responsive Drug-Loaded Nanogel for Synergetic Cancer Therapy”, Polymers-Basel 10, (2018)

C. W. Lin, K. C. Yang, N. C. Cheng, W. B. Tsai, K. L. Lou and J. S. Yu, “Evaluation of adhesion, proliferation, and differentiation of human adipose-derived stem cells on keratin”, J Polym Res 25, (2018)

W. H. Lin, C. Y. Lin, C. C. Tsai, J. S. Yu and W. B. Tsai, “Spheroid Formation of Human Adipose-Derived Stem Cells on Environmentally Friendly BMA/SBMA/HEMA Copolymer-Coated Anti-Adhesive Surface”, B Chem Soc Jpn 91, 1457-1464, (2018)

M. Lu, Y. Liu, Y. C. Huang, C. J. Huang and W. B. Tsai, “Fabrication of photo-crosslinkable glycol chitosan hydrogel as a tissue adhesive”, Carbohyd Polym 181, 668-674, (2018)

S. K. Rajendrakumar, N. C. Chang, A. Mohapatra, S. Uthaman, B. I. Lee, W. B. Tsai and I. K. Park, “A Lipophilic IR-780 Dye-Encapsulated Zwitterionic Polymer-Lipid Micellar Nanoparticle for Enhanced Photothermal Therapy and NIR-Based Fluorescence Imaging in a Cervical Tumor Mouse Model”, Int J Mol Sci 19, (2018)

Y. J. Yang, X. L. Wang, T. C. Huang, X. H. Hu, N. Kawazoe, W. B. Tsai, Y. N. Yang and G. P. Chen, “Regulation of mesenchymal stem cell functions by micro-nano hybrid patterned surfaces”, J Mater Chem B 6, 5424-5434, (2018)

I. N. Ahmed, R. Chang, M. C. Keng, H. W. Chien, H. Y. Chen and W. B. Tsai, “Immobilization of functional polymers on poly(4-benzoyl-pxylylene-co-p-xylylene) films via photochemical conjugation for modulation of cell adhesion”, Colloid Surface B 174, 360-366, (2019)

W. H. Chen, T. Y. Liao, H. Thissen and W. B. Tsai, “One-Step Aminomalononitrile-Based Coatings Containing Zwitterionic Copolymers for the Reduction of Biofouling and the Foreign Body Response”, Acs Biomater Sci Eng 5, 6454-6462, (2019)

Q. H. Cui, T. H. Le, Y. J. Lin, Y. B. Miao, I. T. Sung, W. B. Tsai, H. Y. Chan, Z. H. Lin and H. W. Sung, “A self-powered battery-driven drug delivery device that can function as a micromotor and galvanically actuate localized payload release”, Nano Energy 66, (2019)

Y. Liu, S. C. Ng, J. S. Yu and W. B. Tsai, “Modification and crosslinking of gelatin-based biomaterials as tissue adhesives”, Colloid Surface B 174, 316-323, (2019)

P. T. Wu, C. L. Lin, C. W. Lin, N. C. Chang, W. B. Tsai and J. S. Yu, “Methylene-Blue-Encapsulated Liposomes as Photodynamic Therapy Nano Agents for Breast Cancer Cells”, Nanomaterials-Basel 9, (2019)

Yeh, Shang-Lin; Deval, Piyush; Wu, Jhih-Guang; Luo, Shyh-Chyang; Tsai, Wei-Bor, One-step electrochemical deposition of antifouling polymers with pyrogallol for biosensing applications, Journal Of Materials Chemistry B, 2021

Yeh, Shang-Lin; Wang, Ting-Ching; Yusa, Shin-ichi; Thissen, Helmut; Tsai, Wei-Bor, Conjugation of Polysulfobetaine via Poly(pyrogallol) Coatings for Improving the Antifouling Efficacy of Biomaterials, Acs Omega, 5(3517),3524-9, Feb 2021.

Wang, Ting-Ching; Tsai, Wei-Bor, A biphasic mathematical model for the release of polymer-drug conjugates from poly(vinyl alcohol) hydrogels, Journal Of The Taiwan Institute Of Chemical Engineers, 135, 2022 FEB.

Deval, Piyush; Lin, Chia-Hsuan; Tsai, Wei-Bor, Fabrication of Polysulfobetaine Gradient Coating via Oxidation Polymerization of Pyrogallol To Modulate Biointerfaces, Acs Omega, 7(8),7125-7133, 2022 SEP.

Chien, Hsiu-Wen; Wu, Jen-Chia; Chang, Ying-Chih; Tsai, Wei-Bor, Polycarboxybetaine-Based Hydrogels for the Capture and Release of Circulating Tumor Cells, Gels, 8(7), 2022 DEC

Sun, Yi-Chen; Wu, Li-Li; Chang, Yu-An; Li, Tzu-Yun; Lin, Yang; Hu, Fung-Rong; Tsai, Wei-Bor; Hung, Kai-Feng, Zwitterionic poly(carboxybetaine methacrylate) (polyCBMA) decreases desiccating damage to corneal epithelial cells, Colloid And Interface Science Communications, 50, 2022 MAR.

Ilona Uzieliene, Daiva Bironaite, Jolita Pachaleva, Edvardas Bagdonas, Arkadij Sobolev, Wei-Bor Tsai, Giedrius Kvedaras, Eiva Bernotiene. Chondroitin Sulfate-Tyramine-Based Hydrogels for Cartilage Tissue Repair. Int J Mol Sci. 2023. 24(4):3451. doi: 10.3390/ijms24043451.

Ilona Uzieliene, Daiva Bironaite, Edvardas Bagdonas, Jolita Pachaleva, Arkadij Sobolev, Wei-Bor Tsai, Giedrius Kvederas, Eiva Bernotiene. The Effects of Mechanical Load on Chondrogenic Responses of Bone Marrow Mesenchymal Stem Cells and Chondrocytes Encapsulated in Chondroitin Sulfate-Based Hydrogel. Int J Mol Sci. 2023. 24(3):2915. doi: 10.3390/ijms24032915.

Tsai WB, Ahmed IN. The Impact of Polyethylene Glycol-Modified Chitosan Scaffolds on the Proliferation and Differentiation of Osteoblasts. Int J Biomater. 2023:4864492. doi: 10.1155/2023/4864492.

台大化工系網站英文版

蔡偉博 教授 / Wei-Bor Tsai Professor

蔡偉博 教授 / Wei-Bor Tsai Professor

蔡偉博教授 / Wei-Bor Tsai Professor

蔡偉博教授 / Wei-Bor Tsai Professor