NTUBST2019

• 國立台灣大學 農業化學研究所 博士 (1978/09 ~ 1984/06)
• 國立台灣大學 農業化學研究所 碩士 (1976/09 ~ 1978/06)
• 國立台灣大學 農業化學系 學士 (1972/09 ~ 1976/06)
• 台北市第一女子高級中學 (1969/09 ~ 1972/06)

近年來以保健功能的分子機制為工具，篩選具保健功能潛力的食材或天然物（如中草藥）。再以細胞及動物模式針對篩選出之材料進一步確證其保健功能與作用機制，並追蹤其可能之有效成分及加工製程。在山苦瓜已分離純化鑑定出多種PPAR活性化合物，在山藥、苜蓿芽與山苦瓜皆分離純化鑑定出植物雌激素化合物。這些材料可用於此等活性相關之保健功能，如代謝症候群、更年期與停經後婦女保健，甚至皮膚保健等。目前研究焦點是山苦瓜、褐藻素對代謝異常，尤其是肥胖、代謝症候群等之防治。

• 亞洲營養科學聯盟理事會 理事 (2015/06 ~ now)
• 台灣大學生化科技學系暨研究所 教授 (2009/08 ~ 2019/06)
• 弘光科技大學營養系暨營養醫學研究所 特聘教授 (2009/08 ~ 2012/07)
• 亞洲營養科學聯盟 秘書長 (2007/09 ~ 2011/09)
• 台灣營養學會 理事長 (2006/07 ~ 2009/06)
• 第10屆亞洲營養大會 秘書長 (2003/09 ~ 2007/09)
• 台灣大學生化科技學系 教授兼系主任 (2003/08 ~ 2009/07)
• 台灣大學微生物與生化學研究所 教授 (2003/08 ~ 2009/07)
• 台灣大學農業化學系 教授 (1990/08 ~ 2003/08)
• 瑞典 Karolinska Institute, Center for Biotechnology  訪問學者 (1996/08 ~ 1997/08)
• 美國國立衛生研究院 研究員 (1989/07 ~ 1990/06)
• 台灣大學農業化學系 副教授 (1985/08 ~ 1990/07)
• 台灣大學農業化學系 講師 (1985/03  ~ 1985/07)
• 台灣大學農業化學系 助教 (1984/03 ~ 1985/02)
• 美國 Colorado State Univ., Dept. Food Science and Human Nutrition 訪問學者 (1984/03~1985/02)
• 美國 Rochester 大學毒物系 Technician (1983/06~1984/01)

• 國際營養學聯合會 會士(2009)
• 台灣營養學會 傑出研究貢獻獎(2005)
• 國立台灣大學 研究貢獻獎(2004)
• 台灣農化學會 學術獎(2003)
• 國科會 優等獎及甲種獎助(1991 ~ 2003)
• 中華民國營養學會 陳尚球教授獎(1990)
• 美國油化學家學會 年度最佳論文獎(1988)
• 美國國家衛生研究院 John E. Fogarty 中心國際博士後研究獎學金(1988)

1. Wu MT, Su HM, Cui Y, Windust A, Chou HN, Huang CJ. Fucoxanthin Enhances Chain Elongation and Desaturation of Alpha-Linolenic Acid in HepG2 Cells. Lipids. 2015; 50(10): 945-53.(SCI)
2. Huang WC, Tsai TH, Huang CJ, Li YY, Chyuan JH, Chuang LT, Tsai PJ. Inhibitory effects of wild bitter melon leaf extract on Propionibacterium acnes-induced skin inflammation in mice and cytokine production in vitro. Food Funct 2015; 6(8): 2550-60.(SCI)
3. Lynn KS, Cheng ML, Chen YR, Hsu C, Chen A, Lih TM, Chang HY, Huang CJ, Shiao MS, Pan WH, Sung TY, Hsu WL. Metabolite identification for mass spectrometry-based metabolomics using multiple types of correlated ion information. Anal Chem 2015; 87(4): 2143-51.(SCI)
4. Tsai TH, Huang CJ, Wu WH, Huang WC, Chyuan JH, Tsai PJ. Antioxidant, cell-protective, and anti-melanogenic activities of leaf extracts from wild bitter melon (＂Momordica charantia＂ Linn. var. ＂abbreviata＂ Ser.) cultivars. Bot Stud 2014; 55: 32-51.(SCI)
5. Chang CI, Li YC, Yang CS, Chao CY, Li YJ, Chang HS, Huang CJ, Kuo CC, Kuo YH. Two New Labdane-Type Diterpene Acids from the Wood of Cunninghamia konishii. Helvetica Chimica Acta 2015; 98(1): 123-7.
6. Huang GJ, Deng JS, Chen CC, Huang CJ, Sung PJ, Huang SS, Kuo YH. Methanol extract of Antrodia camphorata protects against lipopolysaccharide-induced acute lung injury by suppressing NF-kappaB and MAPK pathways in mice. J Agric Food Chem 2014; 62(23): 5321-9.(SCI)
7. Lu KH, Tseng HC, Liu CT, Huang CJ, Chyuan JH, Sheen LY. Wild bitter gourd protects against alcoholic fatty liver in mice by attenuating oxidative stress and inflammatory responses. Food Funct 2014; 5(5): 1027-37.(SCI)
8. Wu MT, Chou HN, Huang CJ. Dietary fucoxanthin increases metabolic rate and upregulated mRNA expressions of the PGC-1alpha network, mitochondrial biogenesis and fusion genes in white adipose tissues of mice. Mar Drugs. 2014; 12(2): 964-82.(SCI)
9. Wu-Wong JR, Kawai M, Chen YW, Wessale JL, Huang CJ, Wu MT, Nakane M. Two novel vitamin D receptor modulators with similar structures exhibit different hypercalcemic effects in 5/6 nephrectomized uremic rats. Am J Nephrol 2013; 37(4): 310-9.(SCI)
10. Lu KN, Hsu C, Chang ML, Huang Cj. Wild bitter gourd increased metabolic rate and up-regulated genes related to mitochondria biogenesis and UCP-1 in mice. J Funct Foods 2013; 5(2): 668-78.(SCI)
11. Huang Tn, Lu KN, Pai YP, Chin Hsu, Huang Cj. Role of GLP-1 in the Hypoglycemic Effects of Wild Bitter Gourd. Evid Based Complement Alternat Med. 2013; 2013(Article ID 625892): 13.(SCI)
12. Tsai CH, Chen EC, Tsay HS, Huang CJ. Wild bitter gourd improves metabolic syndrome: a preliminary dietary supplementation trial. Nutr J. 2012; 11: 4. (SCI)
13. Hsu C, Tsai TH, Li YY, Wu WH, Huang CJ, Tsai PJ. Wild bitter melon (Momordica charantia Linn. var. abbreviata Ser.) extract and its bioactive components suppressPropionibacterium acnes-induced inflammation. Food Chem. 2012; 135(3): 976-84. (SCI)
14. Hsu C, Hsieh CL, Kuo YH, Huang CJ. Isolation and identification of cucurbitane-type triterpenoids with partial agonist/antagonist potential for estrogen receptors fromMomordica charantia. J Agric Food Chem. 2011; 59(9): 4553-61. (SCI)
15. Hong YH, Wang SC, Hsu C, Lin BF, Kuo YH, Huang CJ. Phytoestrogenic compounds in alfalfa sprout (Medicago sativa) beyond coumestrol. J Agric Food Chem. 2011; 59(1): 131-7. (SCI)
16. Cui Y, Fraser C, Gardner G, Huang CJ, Reith M, Windust AJ. Isolation and optimisation of the oleaginous yeast Sporobolomyces roseus for biosynthesis of (13)C isotopically labelled 18-carbon unsaturated fatty acids and trans 18:1 and 18:2 derivatives through synthesis. J Ind Microbiol Biotechnol. 2011. (SCI)
17. Chen KJ, Pan WH, Huang CJ, Lin BF. Association between folate status, diabetes, antihypertensive medication and age-related cataracts in elderly Taiwanese. J Nutr Health Aging. 2011; 15(4): 304-10. (SCI)
18. Chen GC, Huang CY, Chang MY, Chen CH, Chen SW, Huang CJ, Chao PM. Two unhealthy dietary habits featuring a high fat content and a sucrose-containing beverage intake, alone or in combination, on inducing metabolic syndrome in Wistar rats and C57BL/6J mice. Metabolism. 2011; 60(2): 155-64. (SCI)
19. Chao CY, Yin MC, Huang CJ. Wild bitter gourd extract up-regulates mRNA expression of PPARalpha, PPARgamma and their target genes in C57BL/6J mice. J Ethnopharmacol. 2011; 135(1): 156-61. (SCI)
20. 蔡崇煌, 陳靖棻, 蔡新聲, 黃青真. 苦瓜於血糖控制之功效及安全性回顧. 臺灣營養學會雜誌. 2010; 35卷3期: 頁115-26.
21. Wu WH, Wang SH, Kuan, II, Kao YS, Wu PJ, Liang CJ, et al. Sesamin attenuates intercellular cell adhesion molecule-1 expression in vitro in TNF-alpha-treated human aortic endothelial cells and in vivo in apolipoprotein-E-deficient mice. Mol Nutr Food Res. 2010; 54(9): 1340-50.(SCI)
22. Hong YH, Huang CJ, Wang SC, Lin BF. The ethyl acetate extract of alfalfa sprout ameliorates disease severity of autoimmune-prone MRL-lpr/lpr mice. Lupus. 2009; 18(3): 206-15. (SCI)
23. Wahlqvist ML, Keatinge JD, Butler CD, Friel S, McKay J, Easdown W, Kuo KN, Huang CJ, Pan WH, Yang RY, Lee MS, Chang HY, Chiu YW, Jaron D, Krawinkel M, Barlow S, Walsh G, Chiang TL, Huang PC, Li D. A Food in Health Security (FIHS) platform in the Asia-Pacific Region: the way forward. Asia Pac J Clin Nutr. 2009; 18(4): 688-702.(SCI)
24. Wu WH, Lin BY, Kuo YH, Huang Cj. Triglycerides constituted of short and medium chain fatty acids and dicarboxylic acids in Momordica charantia, as well as capric acid, inhibit PGE2 production in RAW264.7 macrophages. Food Chem. 2009; 117(2): 306-11.(SCI).(NSC 95-2317-B-003-001)
25. Chen Hl, Hong Lt, Lee JK, Huang Cj. The bone-protective effect of a Taiwanese yam (Dioscorea alata L. cv. Tainung No.2) in ovariectomised female BALB/C mice. J Sci Food Agric. 2009; 89(3): 517-22.(SCI).(NSC 92-2321-B-002-011; 93-2321-B-002-012)
26. Wahlqvist ML, Li D, Sun JQ, Ge K, Paik HY, Cho SH, Lee SK, Huang CJ, Lee MS. Nutrition leadership training in North-East Asia: an IUNS initiative in conjunction with nutrition societies in the region. Asia Pac J Clin Nutr. 2008; 17(4): 672-82.(SCI)
27. Wahlqvist ML, Lee MS, Lau J, Kuo KN, Huang CJ, Pan WH, Chang HY, Chen R, Huang YC. The opportunities and challenges of evidence-based nutrition (EBN) in the Asia Pacific region: clinical practice and policy-setting. Asia Pac J Clin Nutr. 2008; 17(1): 2-7. (SCI)
28. Huang HL, Hong YW, Wong YH, Chen YN, Chyuan JH, Huang CJ, Chao PM. Bitter melon (Momordica charantia L.) inhibits adipocyte hypertrophy and down regulates lipogenic gene expression in adipose tissue of diet-induced obese rats. Br J Nutr. 2008; 99(2): 230-9. (SCI)
29. Hong YH, Wang TC, Huang CJ, Cheng WY, Lin BF. Soy isoflavones supplementation alleviates disease severity in autoimmune-prone MRL-lpr/lpr mice. Lupus. 2008; 17(9): 814-21. (SCI)
30. Chao CY, Huang CJ. In vitro activation of peroxisome proliferator activated receptor alpha by some extracts from food materials. J Food Drug Anal. 2008; 16(4): 62-9. (SCI)
31. Li YJ, Luo SC, Lee YJ, Lin FJ, Cheng CC, Wein YS, Kuo YH, Huang CJ. Isolation and identification of α-CEHC sulfate in rat urine and an improved method for the determination of conjugated α-CEHC. J Agric Food Chem. 2008; 56(23): 11105-13.(SCI).(NSC 90-2320-B-002-102)
32. Hsu SC, Huang CJ. Changes in liver PPARalpha mRNA expression in response to two levels of high-safflower-oil diets correlate with changes in adiposity and serum leptin in rats and mice. J Nutr Biochem. 2007; 18(2): 86-96. (SCI)
33. Cheng WY, Kuo YH, Huang CJ. Isolation and identification of novel estrogenic compounds in yam tuber (Dioscorea alata Cv. Tainung No. 2). J Agric Food Chem. 2007; 55(18): 7350-8. (SCI)
34. Chao PM, Huang HL, Liao CH, Huang ST, Huang CJ. A high oxidised frying oil content diet is less adipogenic, but induces glucose intolerance in rodents. Br J Nutr. 2007; 98(1): 63-71. (SCI)
35. Kuo LC, Cheng WY, Wu RY, Huang CJ, Lee KT. Hydrolysis of black soybean isoflavone glycosides by Bacillus subtilis natto. Appl Microbiol Biotechnol. 2006; 73(2): 314-20. (SCI)
36. Hsu SC, Huang CJ. Reduced fat mass in rats fed a high oleic acid-rich safflower oil diet is associated with changes in expression of hepatic PPARalpha and adipose SREBP-1c-regulated genes. J Nutr. 2006; 136(7): 1779-85. (SCI)
37. Hsieh CC, Huang CJ, Lin BF. Low and high levels of alpha-tocopherol exert opposite effects on IL-2 possibly through the modulation of PPAR-gamma, IkappaBalpha, and apoptotic pathway in activated splenocytes. Nutrition. 2006; 22(4): 433-40. (SCI)
38. Chuang CY, Hsu C, Chao CY, Wein YS, Kuo YH, Huang CJ. Fractionation and identification of 9c, 11t, 13t-conjugated linolenic acid as an activator of PPARalpha in bitter gourd (Momordica charantia L.). J Biomed Sci. 2006; 13(6): 763-72. (SCI)
39. Lin SY, Sheu WH, Chen WY, Lee FY, Huang CJ. Stimulated resistin expression in white adipose of rats with bile duct ligation-induced liver cirrhosis: relationship to cirrhotic hyperinsulinemia and increased tumor necrosis factor-alpha. Mol Cell Endocrinol. 2005; 232(1-2): 1-8. (SCI)
40. Lin SY, Chen WY, Lee FY, Huang CJ, Sheu WH. Activation of ubiquitin-proteasome pathway is involved in skeletal muscle wasting in a rat model with biliary cirrhosis: potential role of TNF-alpha. Am J Physiol Endocrinol Metab. 2005; 288(3): E493-501. (SCI)
41. Cheng WY, Fu ML, Wen LJ, Chen C, Pan WH, Huang CJ. Plasma retinol and a-tocopherol status of the Taiwanese elderly population. Asia Pac J Clin Nutr. 2005; 14(3): 256-62. (SCI)
42. Chao PM, Yang MF, Tseng YN, Chang KM, Lu KS, Huang CJ. Peroxisome proliferation in liver of rats fed oxidized frying oil. J Nutr Sci Vitaminol (Tokyo). 2005; 51(5): 361-8. (SCI)
43. Chao PM, Hsu SC, Lin FJ, Li YJ, Huang CJ. The up-regulation of hepatic acyl-CoA oxidase and cytochrome P450 4A1 mRNA expression by dietary oxidized frying oil is comparable between male and female rats. Lipids. 2004; 39(3): 233-8. (SCI
44. Chao CY, Huang CJ. Bitter gourd (Momordica charantia) extract activates peroxisome proliferator-activated receptors and upregulates the expression of the acyl CoA oxidase gene in H4IIEC3 hepatoma cells. J Biomed Sci. 2003; 10(6 Pt 2): 782-91. (SCI)
45. 劉珍芳, 駱菲莉, 王慈圓, 陳巧明, 蕭寧馨, 高美丁, 莊佳穎, 黃青真. 均衡飲食中維生素E、硒、礦物質及一般營養成分分析. 中華民國營養學會雜誌. 2002; 27卷4期:頁221-31.
46. Huang CJ, Wu MC. Differential effects of foods traditionally regarded as 'heating' and 'cooling' on prostaglandin E(2) production by a macrophage cell line. J Biomed Sci. 2002; 9(6 Pt 2): 596-606. (SCI)
47. 趙蓓敏, 黃青真. 15-deoxy-Δ12,14-PGJ2 對 3T3-L1 前脂肪細胞分化之影響. 中國醫藥科學雜誌. 2001; 2卷2期: 頁117-24.
48. Wu Mc, Huang Cj. Inhibition of prostaglandin E2 production of a macrophage cell line by some phytochemicals. Food Sci Agric Chem. 2001; 3(2): 59-71.
49. Chao PM, Chao CY, Lin FJ, Huang C. Oxidized frying oil up-regulates hepatic acyl-CoA oxidase and cytochrome P450 4 A1 genes in rats and activates PPARalpha. J Nutr. 2001; 131(12): 3166-74. (SCI)
50. 莊艾玲, 潘子明, 洪慧萍, 黃青真. 含寡糖飲料對大白鼠腸道菌相之影響. 中華民國營養學會雜誌. 2000; 25(4): 232-42.
51. Shaw HM, Huang CJ. Secretion of alpha-tocopherol in VLDL is decreased by dietary protein insufficiency in young growing rats. J Nutr. 2000; 130(12): 3050-4. (SCI)
52. Huang C, Tang YL, Chen CY, Chen ML, Chu CH, Hseu CT. The bioavailability of beta-carotene in stir- or deep-fried vegetables in men determined by measuring the serum response to a single ingestion. J Nutr. 2000; 130(3): 534-40. (SCI)
53. 湯雅理, 黃青真. 炸油飲食降低血漿與肝臟維生素a含量. 中華民國營養學會雜誌. 1998; 23(3): 265-79.
54. 朱哲輝, 黃青真. 餵食炸油降低飲食β-胡蘿蔔素於大鼠體內之維生素Ａ價值. 中華民國營養學會雜誌. 1998; 23(3): 281-95.
55. Shaw HM, Huang C. Liver alpha-tocopherol transfer protein and its mRNA are differentially altered by dietary vitamin E deficiency and protein insufficiency in rats. J Nutr. 1998; 128(12): 2348-54. (SCI)
56. Huang CJ, Feltkamp D, Nilsson S, Gustafsson JA. Synergistic activation of RLD-1 by agents triggering PKA and PKC dependent signalling. Biochem Biophys Res Commun. 1998; 243(3): 657-63. (SCI)

專利

1. 黃青真, 吳夢婷, 周宏農, 張美鈴, 細胞內肝X受體調節劑及其用途. 中華民國I 501765. 2015(2015/10/01~2034/03/02).
2. 黃青真, 黃婷妮, 白依平. 苦味化合物於活化GLP-1分泌之用途. 中華民國 I 495464. 2015(2015/08~2033/02).
3. Huang Cj, Wu Mt, Chou Hn, Chang Ml, Composition for regulation of Liver X Receptor(細胞內肝X受體調節劑及其用途). USA US 9,056,091 B1. 2015 (2015/06/16~2034/06/16).
4. 黃青真, 呂侃霓, 蔡新聲, 陳靖棻, 蔡崇煌. 細胞內粒線體之調節劑. 美國US 8,652,539 B1. 2014(2014/02~2032/12).
5. 黃青真, 郭悅雄, 徐瑨. 葫蘆烷型三萜類化合物、醫藥組成物、用途及其萃取方法. 美國US 8,669,244 B2. 2014(2014/03~2032/03).
6. 黃青真, 郭悅雄, 徐瑨, 葫蘆烷型三萜類化合物、醫藥組成分、用途及其萃取方法. 中華民國 I 395587. 2013(2013/05/11~2031/03/31).
7. 黃青真, 鄭瑋宜, 郭悅雄, 江一民, 活化雌激素受體之醫藥組成物. 中華民國 I 373334. 2012 (2012/10/01~2026/09/26).
8. 黃青真, 王思晴, 郭悅雄, 洪永翰, 林璧鳳, 徐瑨, 具雌激素活性之化合物及其應用. 中華民國 I 367210. 2012 (2012/07/01~2028/11/16).
9. 李昆達、黃青真、郭倫甄, 製備去葡萄糖苷大豆異黃酮之方法. 中華民國 I 377254. 2012.
10. 黃青真, 鄭瑋宜, 郭悅雄, 江一民, γ-生育醇-9 (γ-tocopherol-9)在製備活化人類雌激素受體之藥物的用途. 中華民國 I 351951. 2011 (2011/11/11~2026/09/26).
11. Huang Cj, Wang SC, Kuo YH, Hong YH, Lin BF, Hsu C, Estrogenic-active compounds and application thereof(具雌激素活性之化合物及其應用). USA US 7,902,384 B2. 2011 (2011/03/08~2029/4/28).
12. Huang Cj, Cheng WY, Kuo YH, Chiang YM, Compounds having estrogenic activity(一種具雌激素活性之化合物). USA US 7,999,004 B2. 2011 (2011/08/16~2030/02/09).